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dc.contributor.authorKioko Guzmán-Ramos, 0000-0002-5180-4127-
dc.contributor.authorPascal Morin, Jean, 0000-0001-8221-4982-
dc.contributor.otherBermudez Rattoni, Federico-
dc.date.accessioned2018-05-30T21:02:08Z-
dc.date.available2018-05-30T21:02:08Z-
dc.date.issued2015-
dc.identifier.otherhttp://dx.doi.org/10.1155/2015/184083-
dc.identifier.urihttp://hdl.handle.net/20.500.12222/38-
dc.descriptionThe mainstream view on the neurobiological mechanisms underlying memory formation states that memory traces reside on the network of cells activated during initial acquisition that becomes active again upon retrieval (reactivation). These activation and reactivation processes have been called “conjunctive trace.” This process implies that singular molecular events must occur during acquisition, strengthening the connection between the implicated cells whose synchronous activity must underlie subsequent reactivations. The strongest experimental support for the conjunctive trace model comes from the study of immediate early genes such as c-fos, zif268, and activity-regulated cytoskeletal-associated protein. The expressions of these genes are reliably induced by behaviorally relevant neuronal activity and their products often play a central role in long-term memory formation. In this review, we propose that the peculiar characteristics of Arc protein, such as its optimal expression after ongoing experience or familiar behavior, together with its versatile and central functions in synaptic plasticity could explain how familiarization and recognition memories are stored and preserved in the mammalian brain.es_MX
dc.formatapplication/pdfes_MX
dc.languageenges_MX
dc.publisherHindawi Publishing Corporationes_MX
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttps://creativecommons.org/licenses/by/3.0/es_MX
dc.subjectBIOLOGÍA Y QUÍMICAes_MX
dc.titleNew insights on retrieval-induced and ongoing memory consolidation : lessons from arces_MX
dc.typearticlees_MX
dc.rights.licensehttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.rights.licenseinfo:eu-repo/semantics/openAccesses_MX
dc.subject.keywordsMemory Formationes_MX
dc.subject.keywordsARC Proteines_MX
dc.subject.keywordsNeuronal Plasticityes_MX
dc.subject.keywordsSynapseses_MX
dc.subject.keywordsNeuronal Networkes_MX
dc.type.versioninfo:eu-repo/semantics/publishedVersiones_MX
dc.coverageGBes_MX
dc.audienceresearcherses_MX
dc.identificador.materia2es_MX
dc.source.otherNeural Plasticity, vol.2015 (2015)es_MX
dc.source.otherISSN: 2090-5904es_MX
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